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Characterisation of the Timing and Prevalence of Receptor Tyrosine Kinase Expression Changes in Esophageal Carcinogenesis

Paterson AL et al. – The authors provide evidence for a frequent and early role for multiple different receptor tyrosine kinase (RTK) in esophageal carcinogenesis. Given the early timing of receptor deregulation, inhibiting RTKs in preinvasive disease may also represent a novel and effective chemopreventative strategy. [more...]

The Journal of Pathology

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