Physician Assistant News Articles

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The Medical Editors at diligently work around the clock to provide the most current Physician Assistant medical news articles from over 2,000 peer-reviewed clinical journals. Our coverage includes over 32 specialties and 800 subspecialties, perfect for the multidisciplinary practice of today’s PAs. Topics include: everything from Anesthesiology to Women’s Health, plus Economics of Medicine, Popular Press, Teaching Hospital News, and much more. In less than 5 minutes a day, Physician Assistants can be updated with the latest published information from thousands of journals after consulting just one resource.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Endocrine therapy with or without inhibition of epidermal growth factor receptor and human epidermal growth factor receptor 2: A randomized, double-blind, placebo-controlled phase III trial of fulvestrant with or without lapatinib for postmenopausal women with hormone receptor–positive advanced breast cancer Journal of Clinical Oncology, October 30, 2014    Clinical Article

2 Preservation of memory with conformal avoidance of the hippocampal neural stem-cell compartment during whole-brain radiotherapy for brain metastases: A phase II multi-institutional trial Journal of Clinical Oncology, October 30, 2014    Clinical Article

3 Prognostic role of restenosis in 10,004 patients undergoing routine control angiography after coronary stenting European Heart Journal, October 30, 2014    Clinical Article

4 Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK "borderline"-positive rearrangements or a high copy number: A potential major issue for anti-ALK therapeutic strategies Annals of Oncology, October 30, 2014    Clinical Article

5 Effect of n-3 PUFA supplementation on cognitive function throughout the life span from infancy to old age: a systematic review and meta-analysis of randomized controlled trials American Journal of Clinical Nutrition, October 30, 2014    Evidence Based Medicine    Review Article

6 Morbidity in relation to feeding mode in African HIV-exposed, uninfected infants during the first 6 mo of life: the Kesho Bora study American Journal of Clinical Nutrition, October 30, 2014    Clinical Article

7 A comprehensive linear programming tool to optimize formulations of ready-to-use therapeutic foods: an application to Ethiopia American Journal of Clinical Nutrition, October 30, 2014    Clinical Article

8 Adalimumab for the treatment of Japanese patients with intestinal Behcet’s disease Clinical Gastroenterology and Hepatology , October 30, 2014    Clinical Article

9 Telbivudine prevents vertical transmission of hepatitis B virus from women high viral loads: A prospective long-term study Clinical Gastroenterology and Hepatology , October 30, 2014    Clinical Article

10 Alisporivir inhibition of hepatocyte cyclophilins reduces HBV replication and hepatitis B surface antigen production Gastroenterology, October 30, 2014    Clinical Article

11 β-Trace protein: A marker of GFR and other biological pathways American Journal of Kidney Diseases, October 30, 2014    Review Article

12 GFR decline as an alternative end point to kidney failure in clinical trials: A meta-analysis of treatment effects from 37 randomized trials American Journal of Kidney Diseases, October 30, 2014    Evidence Based Medicine    Clinical Article

13 Enhanced chondrogenesis of iPS cells from neonatal-onset multisystem inflammatory disease occurs via the caspase-1-independent cAMP/PKA/CREB pathway Arthritis & Rheumatism, October 30, 2014    Clinical Article

14 An evaluation of risk factors for major adverse cardiovascular events during tocilizumab therapy Arthritis & Rheumatism, October 30, 2014    Clinical Article

15 The diagnosis and management of food allergy and food intolerances Alimentary Pharmacology and Therapeutics, October 30, 2014    Review Article

16 Prevalence and clinical outcome of phrenic nerve injury during superior vena cava isolation and circumferential pulmonary vein antrum isolation using radiofrequency energy American Heart Journal, October 30, 2014    Clinical Article

17 Dietary protein requirement of female adults >65 years determined by the indicator amino acid oxidation technique is higher than current recommendations The Journal of Nutrition, October 30, 2014    Clinical Article

18 Household food insecurity is associated with anemia in adult Mexican women of reproductive age The Journal of Nutrition, October 30, 2014    Clinical Article

19 Artificially and sugar-sweetened carbonated beverage consumption is not associated with risk of lymphoid neoplasms in older men and women The Journal of Nutrition, October 30, 2014    Clinical Article

20 SPADE, a new statistical program to estimate habitual dietary intake from multiple food sources and dietary supplements The Journal of Nutrition, October 30, 2014    Clinical Article

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Highlights in Physician Assistant

GALNT4 predicts survival in patients with ccRCC

As reported in the Journal of Urology, N-acetylgalactosaminyltransferase 4 (GALNT4) levels are decreased in tumor specimens from patients with clear cell renal cell carcinoma (ccRCC; n=104) compared to peritumoral specimens. Decreased expression of GALNT4 is associated with poor OS (OR=3.08) and RFS (OR=2.17). Further, GALNT4 is negatively correlated with tumor size, necrosis, and TNM stage.

YKL-40 predicts poor prognosis for bladder cancer

As reported in Urologic Oncology, the gene expression and serum level of YKL-40 are higher in patients with bladder cancer than healthy controls. Serum YKL-40 levels predict poor prognosis in patients with muscle-invasive bladder cancer (HR=1.75).

CTC count predicts survival in mBC

As reported in The Lancet Oncology, circulating tumor cell (CTC) quantification in patients (20 studies; n = 1944) with metastatic breast cancer (mBC) predicts progression-free survival (PFS) and overall survival (OS), especially when coupled with clinicopathologic data. A CTC count ≥ 5/7.5 mL at baseline is associated with decreased PFS (HR = 1.92) and OS (HR = 2.78). An elevated CTC count 3-5 weeks and 6-8 weeks after treatment commences is also associated with decreased PFS (HR = 1.85 and 2.20) and OS (HR = 2.26 and 2.91).

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