AGEs increase cardiovascular risk in T2DM
As reported in Diabetes, elevated advanced glycation end products increase the risk for incident cardiovascular events (HR=1.31) in type 2 diabetics (n=218).
Risk factors for suicidal ideations in bipolar disorder
As reported in Bipolar Disorders, the following risk factors were associated with suicidal ideations in patients with bipolar disorder (n=130): grade of severity of current episode (OR=22.601); family history of suicide attempt (OR=18.06); preceding life event (OR=3.797); and past history of suicidal event (OR=3.11).
Tapentadol ER effective in alleviating pain of DN
As reported in Diabetes Care, tapentadol ER (100-250 mg bid) for 12 weeks resulted in increased pain relief in patients with moderate-to-severe diabetic neuropathy (n=166) compared to placebo.