1Practical clinical interventions for diet, physical activity, and weight control in cancer survivorsCA: A Cancer Journal for Clinicians  Full Text  Review Article
2IQ and schizophrenia in a Swedish national sample: Their causal relationship and the interaction of IQ with genetic riskAmerican Journal of Psychiatry  Clinical Article
3Functional neuroimaging of avoidance habits in obsessive-compulsive disorderAmerican Journal of Psychiatry  Clinical Article
4Developmental change in amygdala reactivity during adolescence: Effects of family history of depression and stressful life eventsAmerican Journal of Psychiatry  Clinical Article
5Urinary adiponectin is an independent predictor of progression to end-stage renal disease in patients with type 1 diabetes and diabetic nephropathyDiabetes Care  Clinical Article
6The effect of DPT-1 intravenous insulin infusion and daily subcutaneous insulin on endogenous insulin secretion and postprandial glucose toleranceDiabetes Care  Clinical Article
7Multicenter experience using simeprevir and sofosbuvir with or without ribavirin to treat hepatitis C genotype 1 after liver transplantHepatology  Clinical Article
8Bridging the gap between host immune response and intestinal dysbiosis in inflammatory bowel disease: Does IgA mark the spot?Clinical Gastroenterology and Hepatology  Clinical Article
9Benchmarks for operative outcomes of robotic and open radical prostatectomy: Results from the health professionals follow-up studyEuropean Urology  Full Text  Clinical Article
10Systematic review and cumulative analysis of perioperative outcomes and complications after robot-assisted radical cystectomyEuropean Urology  Full Text
1CDC grand rounds: Preventing youth violenceMorbidity and Mortality Weekly Report
2Daclatasvir for hepatitis C: Hint of added benefit in genotype 4German Institute for Quality and Efficiency in Health Care (IQWiG)
3Community quarantine to interrupt Ebola virus transmission - Mawah Village, Bong County, Liberia, August-October, 2014Morbidity and Mortality Weekly Report
4Implementation of Ebola case-finding using a village chieftaincy taskforce in a remote outbreak - Liberia, 2014Morbidity and Mortality Weekly Report
5Notes from the field: Cryptosporidiosis associated with consumption of unpasteurized goat milk - Idaho, 2014Morbidity and Mortality Weekly Report
6Quickstats: Percentage of adults aged 18-64 years who have seen or talked with a mental health professional in the past 12 months, by health insurance status and age group - National Health Interview Survey, United States, 2012-2013Morbidity and Mortality Weekly Report
7ZPower to showcase rechargeable technology for HAs at JDVAC conferenceThe Hearing Review
8Can coffee reduce your risk of MS?American Academy of Neurology News
9New study shows decreased aggressive behavior toward strangers in autism spectrum disorder modelScripps Research Institute News
10First outpatient hip replacement in New York City performed at NYU Langone Medical CenterNYU Langone Medical Center

Show Me:

Tobacco and alcohol use significantly increase risk for ESCC

Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

DCL1 is a tumor suppressor in melanoma patients

As reported in Modern Pathology, down-regulation of cytoplasmic and nuclear DLC1 is associated with poor overall survival and disease-specific 5-y survival in all melanoma patients. Combined down-regulation of cytoplasmic and nuclear DCL1 was associated with the worse survival for patients with metastatic melanoma.

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Clinical Pearls

Clinical Pearl from Smartest DocMarch 31 is the deadline for consumers to enroll in the Health Insurance Marketplace.

Clinical Pearl from Smartest DocNT-proBNP, cortisol and copeptin are independent predictors of short-term functional outcomes in acute ischemic stroke.

Clinical Pearl from Smartest DocThere are currently no approved treatments for Ebola virus so clinical management consists of supportive care.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List