Pharmacy - Pharmacokinetics News & Articles

861 Effects of strong CYP2D6 and 3A4 inhibitors, paroxetine and ketoconazole, on the pharmacokinetics and cardiovascular safety of tamsulosin British Journal of Clinical Pharmacology, April 29, 2011    Clinical Article

862 A semi-physiological population model for prediction of the pharmacokinetics of drugs under liver and renal disease conditions Drug Metabolism and Disposition, April 28, 2011

863 Pharmacokinetics and Pharmacodynamics of Therapeutic Doses of Basal Insulins NPH, Glargine, and Detemir After 1 Week of Daily Administration at Bedtime in Type 2 Diabetes: A randomized cross-over study Full Text Diabetes Care, April 25, 2011    Clinical Article

864 Clinically relevant pharmacokinetic drug interactions in the intensive care unit Intensivmedizin und Notfallmedizin, April 20, 2011

865 Amylin to Present Data Showing Investigational Metreleptin Treatment Led to Long-Term Improvements in Diabetes and Lipid Control in Patients with Lipodystrophy Full Text Amylin Pharmaceuticals, April 18, 2011

866 Drug interactions with phenprocoumon and the risk of serious haemorrhage: a nested case-control study in a large population-based German database European Journal of Clinical Pharmacology, April 18, 2011

867 The Application of Physiologically Based Pharmacokinetic Modelling to Understanding the Clinical Pharmacokinetics of UK-369,003 Drug Metabolism and Disposition, April 15, 2011

868 Pharmacokinetic and Pharmacodynamic Evaluation of the Novel CCR1 Antagonist CCX354 in Healthy Human Subjects: Implications for Selection of Clinical Dose Clinical Pharmacology & Therapeutics, April 15, 2011

869 Safety, Tolerability and Pharmacokinetics of Dalcetrapib Following Single and Multiple Ascending Doses in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Phase I Study Clinical Drug Investigation, April 13, 2011    Clinical Article

870 Metabolism and Pharmacokinetics of Naronapride, a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders Drug Metabolism and Disposition, April 13, 2011

871 Phase I Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4877 in Japanese Patients with Solid Tumors Archives of Drug Information, April 11, 2011

872 Pharmacokinetics of the Long-Acting, First-Generation Antipsychotic Fluphenazine Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 8, 2011

873 Reevaluation of Moxifloxacin Pharmacokinetics and Their Direct Effect on the QT Interval The Journal of Clinical Pharmacology, April 7, 2011

874 Aprepitant Pharmacokinetics and Assessing the Impact of Aprepitant on Cyclophosphamide Metabolism in Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation The Journal of Clinical Pharmacology, April 7, 2011

875 Simulation of Human Intravenous and Oral Pharmacokinetics of 21 Diverse Compounds Using Physiologically Based Pharmacokinetic Modelling Clinical Pharmacokinetics, April 7, 2011

876 A multicenter, randomized, open-label study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients with metastatic colorectal cancer Cancer Chemotherapy and Pharmacology, April 6, 2011    Clinical Article

877 Duloxetine: Clinical Pharmacokinetics and Drug Interactions Clinical Pharmacokinetics, April 5, 2011

878 Pharmacokinetics and Pharmacodynamics of Pegfilgrastim Clinical Pharmacokinetics, April 5, 2011

879 Pharmacokinetics of 17-hydroxyprogesterone caproate in multifetal gestation American Journal of Obstetrics and Gynecology, April 4, 2011

880 Pharmacokinetic considerations in the obese Best Practice & Research Clinical Anaesthesiology, April 1, 2011

1 Anticoagulation revolution: Optimizing care from all angles American Pharmacists Association News, April 5, 2013    Free full text

2 Implementation of a protocol for administration of vancomycin by continuous infusion: pharmacokinetic, pharmacodynamic and toxicological aspects International Journal of Antimicrobial Agents, April 29, 2013

3 Validation of a Novel Approach for Dose Individualization in Pharmacotherapy Using Gabapentin in a Proof of Principles Study Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 8, 2013

4 Pharmacokinetic studies of protein drugs: Past, present and future Advanced Drug Delivery Reviews, April 3, 2013    Review Article

5 A review on estimation of stochastic differential equations for pharmacokinetic/pharmacodynamic models Advanced Drug Delivery Reviews, April 3, 2013    Review Article

6 Drug–Alcohol Interactions American Journal of Lifestyle Medicine, April 11, 2013    Review Article

7 Pharmacokinetic Considerations in Designing Pediatric Studies of Proteins, Antibodies, and Plasma-Derived Products American Journal of Therapeutics, April 9, 2013    Review Article

8 Antifungal therapy: current concepts and evidence-based management Current Medical Research and Opinion, March 4, 2013    Review Article

9 Pharmacokinetics of Doripenem in Infected Patients Treated Within and Outside the Intensive Care Unit Annals of Pharmacotherapy, April 22, 2013

10 Importance of Relating Efficacy Measures to Unbound Drug Concentrations for Anti-Infective Agents Clinical Microbiology Reviews, April 4, 2013

11 Population Pharmacokinetic Analysis of Colistin in Burn Patients Antimicrobial Agents and Chemotherapy, April 18, 2013

12 Population pharmacokinetic of antiepileptic drugs in different populations Central European Journal of Medicine, April 11, 2013

13 Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 2, 2013

14 Prescription Opioid Abuse in the United Kingdom British Journal of Clinical Pharmacology, April 26, 2013

15 The population pharmacokinetics of allopurinol and oxypurinol in patients with gout European Journal of Clinical Pharmacology, March 19, 2013

16 Potentially inappropriate medication use among patients with Alzheimer disease in the REAL.FR cohort: be aware of atropinic and benzodiazepine drugs! European Journal of Clinical Pharmacology, April 25, 2013

17 Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation Journal of Pharmacology and Experimental Therapeutics, January 14, 2013

18 A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers Epilepsy Research, April 16, 2013

19 Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans Drug Metabolism and Disposition, April 1, 2013

20 Dose finding by concentration-response versus dose-response: a simulation-based comparison European Journal of Clinical Pharmacology, February 21, 2013    Review Article