Pharmacy - Dosing News & Articles

841 Effect of loading dose and formulation on safety and efficacy of conivaptan in treatment of euvolemic and hypervolemic hyponatremia American Journal of Health-System Pharmacy, March 28, 2011

842 Phase 2 trial of a novel capecitabine dosing schedule in combination with bevacizumab for patients with metastatic breast cancer Cancer, March 28, 2011    Clinical Article

843 Effects of clinical decision support on initial dosing and monitoring of tobramycin and amikacin American Journal of Health-System Pharmacy, March 28, 2011

844 The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene British Journal of Clinical Pharmacology, March 24, 2011

845 High-Dose Ketorolac Affects Adult Spinal Fusion: A Meta-Analysis of the Effect of Perioperative Nonsteroidal Anti-Inflammatory Drugs on Spinal Fusion Spine, March 24, 2011    Evidence Based Medicine    Clinical Article

846 Analysis of efficacy and cost-effectiveness of high-dose arabinoside versus daunorubicin chemotherapy in older adult patients with acute myeloid leukemia by cytogenetic risk profile: retrospective review from China International Journal of Hematology, March 24, 2011

847 Mechanisms of fingolimods efficacy and adverse effects in multiple sclerosis Annals of Neurology , March 22, 2011    Clinical Article

848 Prevention of peptic ulcers with esomeprazole in patients at risk for ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON) Heart, March 22, 2011    Clinical Article

849 Role of Omeprazole Dosage and Cytochrome P450 2C19 Genotype in Patients Receiving Omeprazole-Amoxicillin Dual Therapy for Helicobacter pylori Eradication Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, March 18, 2011

850 Standard- vs High-Dose Clopidogrel Based on Platelet Function Testing After Percutaneous Coronary Intervention: The GRAVITAS Randomized Trial Full Text JAMA, March 17, 2011    Clinical Article

851 Optimizing initial vancomycin dosing in burn patients Burns, March 16, 2011    Clinical Article

852 Low-Dose Peginterferon Alfa-2a Is Safe and Produces a Sustained Virologic Response in Patients With Chronic Hepatitis C and End-Stage Renal Disease Clinical Gastroenterology and Hepatology , March 16, 2011    Clinical Article

853 Randomised clinical trial: twice daily esomeprazole 40 mg vs. pantoprazole 40 mg in Barretts oesophagus for 1 year Alimentary Pharmacology and Therapeutics, March 14, 2011    Clinical Article

854 Pediatric Dosing Errors Quite Common Full Text U.S. Pharmacist, March 14, 2011

855 Agreement between equations estimating glomerular filtration rate in elderly nursing home residents and in hospitalised patients: implications for drug dosing Age and Aging, March 14, 2011

856 Paliperidone extended-release: does it have a place in antipsychotic therapy Full Text Drug Design, Development and Therapy, March 14, 2011

857 A Large Observational Study of Cardiovascular Outcomes Associated With Atorvastatin or Simvastatin Therapy in Hypertensive Patients Without Prior Cardiovascular Disease American Journal of Therapeutics, March 11, 2011    Clinical Article

858 Urinary Pharmacokinetics and Bactericidal Activity of Finafloxacin (200 and 800 mg) in Healthy Volunteers Receiving a Single Oral Dose Chemotherapy, March 11, 2011

859 Pharmacokinetics of the mono-hydroxy derivative of oxcarbazepine and its enantiomers after a single i.v. dose given as racemate compared with a single oral dose of oxcarbazepine Drug Metabolism and Disposition, March 10, 2011

860 Effect of CYP2C19 Polymorphism on the Pharmacokinetics of Voriconazole After Single and Multiple Doses in Healthy Volunteers The Journal of Clinical Pharmacology, March 10, 2011

1 Once-Weekly Exenatide: An Extended-Duration Glucagon-Like Peptide Agonist for the Treatment of Type 2 Diabetes Mellitus Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 3, 2013

2 Understanding the dose-response relationship of allopurinol: predicting the optimal dosage British Journal of Clinical Pharmacology, April 19, 2013
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3 The danger with cutting medication patches American Pharmacists Association News, March 15, 2013    Free full text

4 Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 2, 2013

5 Risk of Asthma Exacerbation, Asthma-Related Health Care Utilization and Costs, and Adherence to Controller Therapy in Patients with Asthma Receiving Fluticasone Propionate/Salmeterol Inhalation Powder 100µg/50µg Versus Mometasone Furoate Inhalation Powder Journal of Asthma, March 19, 2013

6 Risk Factors for a Low Linezolid Trough Plasma Concentration in Acute Infections Antimicrobial Agents and Chemotherapy, March 29, 2013    Review Article

7 Opioid Overdose: What Hospital Pharmacists Should Know U.S. Pharmacist, April 26, 2013    Free full text

8 High-dose FOLFIRI, Surgery, and Radiofrequency Ablation for Patients with Unresectable Liver Metastases from Colorectal Cancer Anticancer Research, April 9, 2013

9 Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects Drug Development and Industrial Pharmacy, March 26, 2013    Review Article

10 Fixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer Breast Cancer Research and Treatment, April 17, 2013

11 Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial BMC Family Practice, April 18, 2013    Free full text

12 Validation of a Novel Approach for Dose Individualization in Pharmacotherapy Using Gabapentin in a Proof of Principles Study Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 8, 2013

13 Software for Dosage Individualization of Voriconazole for Immunocompromised Patients Antimicrobial Agents and Chemotherapy, March 25, 2013

14 Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa Malaria Journal, April 16, 2013    Free full text    Review Article

15 Efficacy and tolerability of 5-day azacytidine dose-intensified regimen in higher-risk MDS Annals of Hematology, April 22, 2013

16 Citalopram and cardiac toxicity European Journal of Clinical Pharmacology, April 18, 2013    Review Article

17 Dynamic View on Affordability of Fixed-Dose Combination Antihypertensive Drug Therapy American Journal of Hypertension, April 3, 2013

18 Methadone at tapered doses for the management of opioid withdrawal Cochrane Reviews, March 6, 2013    Review Article

19 Efficacy and Plasma Drug Concentrations With Nondaily Dosing of Rosuvastatin Canadian Journal of Cardiology, March 13, 2013

20 Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations BMC Pharmacology & Toxicology, April 15, 2013    Free full text