Pharmacy - Dosing News & Articles

821 Low-Dose Valproic Acid Enhances Radiosensitivity of Prostate Cancer through Acetylated p53-Dependent Modulation of Mitochondrial Membrane Potential and Apoptosis Molecular Cancer Research, April 19, 2011    Clinical Article

822 High-dose clopidogrel does not reduce mortality after PCI Full Text Drug Topics, April 19, 2011

823 High-dose rifaximin treatment alleviates global symptoms of irritable bowel syndrome Full Text Clinical and Experimental Gastroenterology, April 19, 2011    Clinical Article

824 A pharmacodynamic analysis of receptor-based dosing optimization of erythropoietin efficacy Drug Metabolism and Disposition, April 19, 2011

825 A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes : The Lancet Neurology The Lancet Neurology, April 19, 2011    Clinical Article

826 Effects of low dose methotrexate on relapsing-remitting multiple sclerosis comparison to Interferon (beta)-1(alpha): A randomized controlled trial Journal of Research in Medical Sciences, April 18, 2011    Clinical Article

827 Is the Maximum Dose of 90 mg Alteplase Sufficient for Patients With Ischemic Stroke Weighing >100 kg Full Text Stroke, April 18, 2011    Clinical Article

828 Effect of Propranolol on Word Fluency in Autism Cognitive and Behavioral Neurology, April 18, 2011    Clinical Article

829 Pharmacokinetic and Pharmacodynamic Evaluation of the Novel CCR1 Antagonist CCX354 in Healthy Human Subjects: Implications for Selection of Clinical Dose Clinical Pharmacology & Therapeutics, April 15, 2011

830 The Innate Immune Response, Clinical Outcomes, and Ex Vivo HCV Antiviral Efficacy of a TLR7 Agonist (PF-4878691) Clinical Pharmacology & Therapeutics, April 15, 2011

831 A Phase Two Randomised Controlled Double Blind Trial of High Dose Intravenous Methylprednisolone and Oral Prednisolone versus Intravenous Normal Saline and Oral Prednisolone in Individuals with Leprosy Type 1 Reactions and/or Nerve Function Impairment Full Text PLoS Neglected Tropical Diseases, April 15, 2011

832 Open-label, ascending dose, prospective cohort study evaluating the antiviral efficacy of Rosuvastatin therapy in serum and lipid fractions in patients with chronic hepatitis C Journal of Viral Hepatitis, April 14, 2011

833 Efficacy and Safety of a 4-Drug Fixed-Dose Combination Regimen Compared With Separate Drugs for Treatment of Pulmonary Tuberculosis: The Study C Randomized Controlled Trial JAMA, April 13, 2011    Clinical Article

834 A phase I trial of MK-0731, a Kinesin Spindle Protein (KSP) inhibitor, in patients with solid tumors Full Text Investigational New Drugs, April 13, 2011

835 A randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel and CMF versus a standard-dosed epirubicin/cyclophosphamide followed by paclitaxel±darbepoetin alfa in primary breast cancer—results at the time of surgery Full Text Annals of Oncology, April 12, 2011    Clinical Article

836 Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes Full Text Cardiovascular Diabetology, April 7, 2011

837 Reduced-Intensity Conditioning Regimen Combined with Low-Dose Total Body Irradiation in the Treatment of Myelodysplastic Syndrome Acta Haematologica, April 5, 2011

838 Investigational Direct-Acting Antiviral BMS-790052 Plus PEG-Interferon Alfa and Ribavirin Achieved Up to 92% Sustained Virologic Response in Phase II Dose-Ranging Study of Treatment-Naïve Hepatitis C Patients Full Text Bristol Myers-Squibb, April 1, 2011

839 Pediatric Cardiovascular Drug Dosing in Critically Ill Children and Extracorporeal Membrane Oxygenation Journal of Cardiovascular Pharmacology, March 30, 2011

840 Evaluation of Chemotherapy-Induced Severe Myelosuppression Incidence in Obese Patients With Capped Dosing Journal of Oncology Practice, March 29, 2011

1 Once-Weekly Exenatide: An Extended-Duration Glucagon-Like Peptide Agonist for the Treatment of Type 2 Diabetes Mellitus Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 3, 2013

2 Understanding the dose-response relationship of allopurinol: predicting the optimal dosage British Journal of Clinical Pharmacology, April 19, 2013
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3 The danger with cutting medication patches American Pharmacists Association News, March 15, 2013    Free full text

4 Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 2, 2013

5 Risk of Asthma Exacerbation, Asthma-Related Health Care Utilization and Costs, and Adherence to Controller Therapy in Patients with Asthma Receiving Fluticasone Propionate/Salmeterol Inhalation Powder 100µg/50µg Versus Mometasone Furoate Inhalation Powder Journal of Asthma, March 19, 2013

6 Risk Factors for a Low Linezolid Trough Plasma Concentration in Acute Infections Antimicrobial Agents and Chemotherapy, March 29, 2013    Review Article

7 Opioid Overdose: What Hospital Pharmacists Should Know U.S. Pharmacist, April 26, 2013    Free full text

8 High-dose FOLFIRI, Surgery, and Radiofrequency Ablation for Patients with Unresectable Liver Metastases from Colorectal Cancer Anticancer Research, April 9, 2013

9 Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects Drug Development and Industrial Pharmacy, March 26, 2013    Review Article

10 Fixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer Breast Cancer Research and Treatment, April 17, 2013

11 Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial BMC Family Practice, April 18, 2013    Free full text

12 Validation of a Novel Approach for Dose Individualization in Pharmacotherapy Using Gabapentin in a Proof of Principles Study Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 8, 2013

13 Software for Dosage Individualization of Voriconazole for Immunocompromised Patients Antimicrobial Agents and Chemotherapy, March 25, 2013

14 Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa Malaria Journal, April 16, 2013    Free full text    Review Article

15 Efficacy and tolerability of 5-day azacytidine dose-intensified regimen in higher-risk MDS Annals of Hematology, April 22, 2013

16 Citalopram and cardiac toxicity European Journal of Clinical Pharmacology, April 18, 2013    Review Article

17 Dynamic View on Affordability of Fixed-Dose Combination Antihypertensive Drug Therapy American Journal of Hypertension, April 3, 2013

18 Methadone at tapered doses for the management of opioid withdrawal Cochrane Reviews, March 6, 2013    Review Article

19 Efficacy and Plasma Drug Concentrations With Nondaily Dosing of Rosuvastatin Canadian Journal of Cardiology, March 13, 2013

20 Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations BMC Pharmacology & Toxicology, April 15, 2013    Free full text