Pharmacy - Dosing News & Articles

61 Azilsartan Medoxomil/Chlorthalidone: A New Fixed-Dose Combination Antihypertensive Annals of Pharmacotherapy, April 18, 2013    Clinical Article

62 Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors Investigational New Drugs, April 18, 2013    Clinical Article

63 Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial Full Text BMC Family Practice, April 18, 2013    Clinical Article

64 Citalopram and cardiac toxicity European Journal of Clinical Pharmacology, April 18, 2013    Review Article

65 A UGT1A1*28 and *6 genotype-directed phase I dose-escalation trial of irinotecan with fixed-dose capecitabine in Korean patients with metastatic colorectal cancer Cancer Chemotherapy and Pharmacology, April 18, 2013    Clinical Article

66 Drospirenone and non-fatal venous thromboembolism: Is there a risk difference by dosage of Ethinyl-Estradiol Journal of Thrombosis and Haemostasis, April 18, 2013    Clinical Article

67 Pharmacokinetics of Phase I Nevirapine Metabolites following a Single Dose and at Steady State Antimicrobial Agents and Chemotherapy, April 18, 2013    Clinical Article

68 Fixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer Breast Cancer Research and Treatment, April 17, 2013    Clinical Article

69 Efficacy, safety, and pharmacokinetics of imatinib dose escalation to 800mg/day in patients with advanced gastrointestinal stromal tumors Investigational New Drugs, April 17, 2013    Clinical Article

70 Rituximab, bendamustine, and lenalidomide in patients with aggressive B cell lymphoma not eligible for high-dose chemotherapy or anthracycline-based therapy: phase I results of the SAKK 38/08 trial Annals of Hematology, April 17, 2013    Clinical Article

71 Phase I, dose-finding study of AZD8931, an inhibitor of EGFR (erbB1), HER2 (erbB2) and HER3 (erbB3) signaling, in patients with advanced solid tumors Investigational New Drugs, April 17, 2013    Clinical Article

72 Mylan Delivers Much-anticipated One Pill Once a Day Triple Fixed-dose Antiretroviral Combination to the South African National Department of Health Full Text Mylan, April 17, 2013

73 Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa Full Text Malaria Journal, April 16, 2013    Review Article    Clinical Article

74 A phase 1b study of trametinib, an oral Mitogen-activated protein kinase kinase (MEK) inhibitor, in combination with gemcitabine in advanced solid tumours European Journal of Cancer, April 16, 2013    Clinical Article

75 Urolithiasis in patients on high dose felbamate The Journal of Urology, April 16, 2013    Review Article    Clinical Article

76 Phase I-IIa study of BMS-690514, an EGFR, HER-2 and -4 and VEGFR-1 to -3 oral tyrosine kinase inhibitor, in patients with advanced or metastatic solid tumours European Journal of Cancer, April 16, 2013    Clinical Article

77 A Phase II Randomized Dose Escalation Trial of Sorafenib in Patients With Advanced Hepatocellular Carcinoma Full Text The Oncologist, April 15, 2013    Clinical Article

78 Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations Full Text BMC Pharmacology & Toxicology, April 15, 2013

79 Wide intra- and inter-country variability in drug use and dosage in very-low-birth-weight newborns with severe infections European Journal of Clinical Pharmacology, April 12, 2013    Clinical Article

80 Feasibility of adding everolimus to carboplatin and paclitaxel, with or without bevacizumab, for treatment-naive, advanced non-small cell lung cancer Investigational New Drugs, April 12, 2013    Clinical Article

1 Once-Weekly Exenatide: An Extended-Duration Glucagon-Like Peptide Agonist for the Treatment of Type 2 Diabetes Mellitus Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 3, 2013

2 Understanding the dose-response relationship of allopurinol: predicting the optimal dosage British Journal of Clinical Pharmacology, April 19, 2013
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3 The danger with cutting medication patches American Pharmacists Association News, March 15, 2013    Free full text

4 Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 2, 2013

5 Risk of Asthma Exacerbation, Asthma-Related Health Care Utilization and Costs, and Adherence to Controller Therapy in Patients with Asthma Receiving Fluticasone Propionate/Salmeterol Inhalation Powder 100µg/50µg Versus Mometasone Furoate Inhalation Powder Journal of Asthma, March 19, 2013

6 Risk Factors for a Low Linezolid Trough Plasma Concentration in Acute Infections Antimicrobial Agents and Chemotherapy, March 29, 2013    Review Article

7 Opioid Overdose: What Hospital Pharmacists Should Know U.S. Pharmacist, April 26, 2013    Free full text

8 High-dose FOLFIRI, Surgery, and Radiofrequency Ablation for Patients with Unresectable Liver Metastases from Colorectal Cancer Anticancer Research, April 9, 2013

9 Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects Drug Development and Industrial Pharmacy, March 26, 2013    Review Article

10 Fixed-dose capecitabine is feasible: results from a pharmacokinetic and pharmacogenetic study in metastatic breast cancer Breast Cancer Research and Treatment, April 17, 2013

11 Efficacy of high doses of oral penicillin versus amoxicillin in the treatment of adults with non-severe pneumonia attended in the community: study protocol for a randomised controlled trial BMC Family Practice, April 18, 2013    Free full text

12 Validation of a Novel Approach for Dose Individualization in Pharmacotherapy Using Gabapentin in a Proof of Principles Study Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 8, 2013

13 Software for Dosage Individualization of Voriconazole for Immunocompromised Patients Antimicrobial Agents and Chemotherapy, March 25, 2013

14 Creative solutions to extraordinary challenges in clinical trials: methodology of a phase III trial of azithromycin and chloroquine fixed-dose combination in pregnant women in Africa Malaria Journal, April 16, 2013    Free full text    Review Article

15 Efficacy and tolerability of 5-day azacytidine dose-intensified regimen in higher-risk MDS Annals of Hematology, April 22, 2013

16 Citalopram and cardiac toxicity European Journal of Clinical Pharmacology, April 18, 2013    Review Article

17 Dynamic View on Affordability of Fixed-Dose Combination Antihypertensive Drug Therapy American Journal of Hypertension, April 3, 2013

18 Methadone at tapered doses for the management of opioid withdrawal Cochrane Reviews, March 6, 2013    Review Article

19 Efficacy and Plasma Drug Concentrations With Nondaily Dosing of Rosuvastatin Canadian Journal of Cardiology, March 13, 2013

20 Cotrimoxazole plasma levels, dialyzer clearance and total removal by extended dialysis in a patient with acute kidney injury: risk of under-dosing using current dosing recommendations BMC Pharmacology & Toxicology, April 15, 2013    Free full text