Pharmacy - Dosing News & Articles

41 Prospective Phase II Single-Center Study of the Safety of a Single Very High Dose of Liposomal Amphotericin B for Antifungal Prophylaxis in Patients with Acute Myeloid Leukemia Antimicrobial Agents and Chemotherapy, May 17, 2013    Clinical Article

42 Low-Dose Manic Switch and High-Dose Antimanic Effect and Extrapyramidal Symptoms by Aripiprazole in a Single Bipolar Patient American Journal of Therapeutics, May 16, 2013

43 Efficacy and safety of short-term administration of recombinant human atrial natriuretic peptide (rhANP) for congestive heart failure: a phase II, multicentre randomized controlled dose-finding study Journal of Clinical Pharmacy and Therapeutics, May 15, 2013    Clinical Article

44 Can we reduce the dosage of biologics in spondyloarthritis? Autoimmunity Reviews, May 15, 2013    Review Article

45 Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia European Journal of Clinical Pharmacology, May 15, 2013    Clinical Article

46 Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer Cancer Chemotherapy and Pharmacology, May 14, 2013    Clinical Article

47 A phase II study of modified dose-dense paclitaxel and every 4-week carboplatin for the treatment of advanced-stage primary epithelial ovarian, fallopian tube, or peritoneal carcinoma Cancer Chemotherapy and Pharmacology, May 14, 2013    Clinical Article

48 Center of Cancer Systems Biology Second Annual Workshop—Tumor Metronomics: Timing and Dose Level Dynamics Cancer Research, May 14, 2013    Clinical Article

49 Study Design and Rationale of a Dose-Ranging Trial of LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy Full Text Clinical Cardiology, May 13, 2013    Clinical Article

50 Phase I and pharmacokinetic study of IV vinflunine in cancer patients with liver dysfunction Investigational New Drugs, May 10, 2013    Clinical Article

51 Feasibility and dose discovery analysis of zoledronic acid with concurrent chemotherapy in the treatment of newly diagnosed metastatic osteosarcoma European Journal of Cancer, May 10, 2013    Clinical Article

52 Three-phase adaptive dose-painting-by-numbers for head-and-neck cancer: initial results of the phase I clinical trial Radiotherapy & Oncology, May 10, 2013    Clinical Article

53 A Phase 1 dose-escalation study of the safety and pharmacokinetics of once-daily oral foretinib, a multi-kinase inhibitor, in patients with solid tumors Investigational New Drugs, May 9, 2013    Clinical Article

54 Phase I trial of the combination of the Akt inhibitor nelfinavir and chemoradiation for locally advanced rectal cancer Radiotherapy & Oncology, May 9, 2013    Clinical Article

55 Evaluation of medication dose alerts in pediatric inpatients International Journal of Medical Informatics, May 9, 2013    Review Article

56 Bifocal intracranial tumors of nongerminomatous germ cell etiology: diagnostic and therapeutic implications Neuro-Oncology, May 9, 2013    Clinical Article

57 Metronomic chemotherapy following the maximum tolerated dose is an effective anti-tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells International Journal of Cancer, May 9, 2013    Clinical Article

58 A Phase I first-in-human study with tefinostat- a monocyte/macrophage targeted histone deacetylase inhibitor - in patients with advanced haematological malignancies British Journal of Haematology, May 9, 2013    Clinical Article

59 Phase I study of PM00104 (Zalypsis) administered as a 1-hour weekly infusion resting every fourth week in patients with advanced solid tumors Investigational New Drugs, May 8, 2013    Clinical Article

60 Sarepta Therapeutics Initiates Dosing in Phase I Multiple Ascending Dose Study of Drug for Treatment of Marburg Virus Full Text Sarepta Therapeutics, May 8, 2013

1 Antibiotic Therapy: Adverse Effects and Dosing Considerations U.S. Pharmacist, May 1, 2013    Free full text

2 Opioid Overdose: What Hospital Pharmacists Should Know U.S. Pharmacist, April 26, 2013    Free full text

3 Prospective Phase II Single-Center Study of the Safety of a Single Very High Dose of Liposomal Amphotericin B for Antifungal Prophylaxis in Patients with Acute Myeloid Leukemia Antimicrobial Agents and Chemotherapy, May 17, 2013

4 Once-Weekly Exenatide: An Extended-Duration Glucagon-Like Peptide Agonist for the Treatment of Type 2 Diabetes Mellitus Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 3, 2013

5 Use of Oral Direct Factor Xa Inhibiting Anticoagulants in Elective Hip and Knee Arthroplasty: A Meta-analysis of Efficacy and Safety Profiles Compared with those of Low-Molecular-Weight Heparins Current Vascular Pharmacology, May 30, 2013    Evidence Based Medicine    Review Article

6 The danger with cutting medication patches American Pharmacists Association News, March 15, 2013    Free full text

7 First human dose-escalation study with remogliflozin etabonate, a selective inhibitor of the sodium-glucose transporter 2 (SGLT2), in healthy subjects and in subjects with type 2 diabetes mellitus BMC Pharmacology & Toxicology, May 20, 2013    Free full text

8 Association between adverse reactions to allopurinol and exposures to high maintenance doses: implications for management of patients using allopurinol JCR: Journal of Clinical Rheumatology, May 23, 2013

9 Glomerular Filtration Rate Equations Overestimate Creatinine Clearance in Older Individuals Enrolled in the Baltimore Longitudinal Study on Aging: Impact on Renal Drug Dosing Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, May 2, 2013

10 Impact of Chemotherapy-Induced Peripheral Neuropathy on Treatment Delivery in Nonmetastatic Breast Cancer Journal of Oncology Practice, May 1, 2013

11 Understanding the dose-response relationship of allopurinol: predicting the optimal dosage British Journal of Clinical Pharmacology, April 19, 2013
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12 Efficacy and safety of two ramipril and hydrochlorothiazide fixed-dose combination formulations in adults with stage 1 or stage 2 arterial hypertension evaluated by using abpm Clinical Therapeutics, May 24, 2013

13 Software for Dosage Individualization of Voriconazole for Immunocompromised Patients Antimicrobial Agents and Chemotherapy, March 25, 2013

14 Radical prostatectomy versus high dose permanent prostate brachytherapy using iodine-125 seeds for patients with high risk prostate cancer: a matched cohort analysis World Journal of Urology, May 2, 2013    Review Article

15 Ketamine for Chronic Pain: Risks and Benefits British Journal of Clinical Pharmacology, March 4, 2013

16 Low-Dose Manic Switch and High-Dose Antimanic Effect and Extrapyramidal Symptoms by Aripiprazole in a Single Bipolar Patient American Journal of Therapeutics, May 16, 2013

17 Neuromuscular Responses to Incremental Caffeine Doses: Performance and Side Effects Medicine and Science in Sports and Exercise, May 22, 2013    Evidence Based Medicine

18 Evaluation of Renal Drug Dosing: Prescribing Information and Clinical Pharmacist Approaches Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, July 26, 2010

19 Pharmacokinetics of Oltipraz and Its Major Metabolite (RM) in Patients With Liver Fibrosis or Cirrhosis: Relationship With Suppression of Circulating TGF-beta 1 Clinical Pharmacology & Therapeutics, July 22, 2010

20 Dose patterns among patients using low-dose buprenorphine patches Pain Medicine, May 22, 2013