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Synthesis and anticancer activity of 5,6,8,13-tetrahydro-7H-naphtho[2,3-a][3]-benzazepine-8,13-diones Full Text
Archives of Pharmacal Research, 06/21/2012
Phutdhawong W et al. – The results showed that 5,6,8,13–tetrahydro–2,3,4,9–tetramethoxy–7H–naphtho[2,3–a][3]benzazepine–8,13–dione 4g and 5,6,8,13–tetrahydro–2,3,9–trimethoxy–7H–naphtho[2,3–a][3]benzazepine–8,13–dione 4h have significant cytotoxicity against a hepatocellular carcinoma cell line with IC50 = 3.5 μg/mL and 3.0 μg/mL, respectively.
