Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects
Journal of Clinical Pharmacy and Therapeutics, 06/21/2012
Lee S et al. – Dexmedetomidine shows linear pharmacokinetic (PK) characteristics and dose–dependent sedative effects. A two–compartment population PK model was developed for healthy Korean subjects. The PK parameter estimates are similar in Koreans and Caucasians.