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The upregulation of heat shock protein 47 in human gingival fibroblasts stimulated with cyclosporine A
Journal of Periodontal Research, 11/12/09
Chang T–Y et al. – Expression of Hsp47 is significantly upregulated in cyclosporine A–induced gingival overgrowth specimens, and Hsp47 expression induced by cyclosporine A in fibroblasts may be mediated by the MEK signal transduction pathway. The expression of Hsp47 could be significantly enhanced by A. actinomycetemcomitans and interlukin–1alpha.
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