Pharmacy Medical News about Migraine Disorders Trastuzumab

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A Throbbing Pain in the Head: Trastuzumab-induced Migraine
Anticancer Research, 11/06/09

Van Rooij F et al. – Trastuzumab, an epidermal growth factor receptor inhibitor, is used in the treatment of both early–stage and metastatic breast cancer. In general it is well tolerated, with a flu–like syndrome occurring frequently a few hours after administration, including symptoms such as fever, sweating, skin rash, nausea and headache. A migraineous headache however has never been described as an adverse event. Here the authors present a patient in whom a strong relationship between trastuzumab infusion and a migraineous headache syndrome was present, without evidence of metastatic disease. Treatment with corticosteroids for the infusion–related complaints resulted in significant pain relief.

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Topiramate in migraine progression
The Journal of Headache and Pain, 10/21/09 Relevance Score: 69%

CSD, BBB and MMP-9 elevations: animal experiments versus clinical phenomena in migraine
Expert Review of Neurotherapeutics, 11/12/09 Relevance Score: 68%

Controversies in migraine
Nurse Prescribing, 10/09/09 Relevance Score: 68%

Ankle-Brachial Index, a Screening for Peripheral Obstructive Arterial Disease, and Migraine – A Controlled Study
Headache: The Journal of Head and Face Pain, 10/07/09 Relevance Score: 68%

New drugs for migraine
The Journal of Headache and Pain, 10/05/09 Relevance Score: 68%