Pharmacy Medical News about Morphine

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Morphine/naltrexone extended-release capsules (Embeda): Combination of mu-opioid agonist and mu-opioid antagonist approved for the management of moderate-to-severe pain when continuous analgesia is needed for an extended time period
Formulary , 11/02/09

This extended–release capsule contains a combination of morphine, a mu–opioid receptor agonist, and naltrexone, a mu–opioid receptor antagonist. This combination was approved on August 13, 2009, for the management of moderate–to–severe pain when a continuous, around–the–clock opioid analgesic is needed for an extended period of time.

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The INFUSE Morphine Study: Use of Recombinant Human Hyaluronidase (rHuPH20) to Enhance the Absorption of Subcutaneously Administered Morphine in Patients with Advanced Illness
Journal of Pain and Symptom Management, 10/13/09 Relevance Score: 95%

Comparison of the effect of adding remifentanil to patient-controlled tramadol or morphine for postoperative analgesia after major abdominal surgery
Journal of Opioid Management, 11/03/09 Relevance Score: 94%

The INFUSE-Morphine IIB Study: Use of Recombinant Human Hyaluronidase (rHuPH20) to Enhance the Absorption of Subcutaneous Morphine in Healthy Volunteers
Journal of Pain and Symptom Management, 10/13/09 Relevance Score: 94%

Effect of topical morphine (mouthwash) on oral pain due to chemotherapy- and/or radiotherapy-induced mucositis: a randomized double-blinded study
Journal of Palliative Medicine, 10/19/09 Relevance Score: 91%

Analysis of individual patient data from clinical trials: epidural morphine for postoperative pain
British Journal of Anesthesia, 11/05/09 Relevance Score: 90%