Pharmacy Medical News about Nevirapine

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Efficacy of Short-Course AZT Plus 3TC to Reduce Nevirapine Resistance in the Prevention of Mother-to-Child HIV Transmission: A Randomized Clinical Trial
PLoS Medicine, 10/28/09

McIntyre JA et al. – A short course of AZT plus 3TC, supplementing maternal and infant sdNVP, reduces emergent NNRTI resistance mutations in both mothers and their infants. However, this trial was not powered to detect small differences between the CBV arms.

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Viral Load Decay in Antiretroviral-Naïve Patients Receiving Once-Daily Tenofovir and Emtricitabine plus Twice-Daily Nevirapine
HIV Clinical Trials, 11/17/09 Relevance Score: 87%

Pharmacokinetic Assessment of Nevirapine and Metabolites in Human Immunodeficiency Virus Type 1-Infected Patients with Hepatic Fibrosis
Antimicrobial Agents and Chemotherapy, 10/09/09 Relevance Score: 87%

Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
Drug Metabolism and Disposition, 10/06/09 Relevance Score: 85%

Response to Nonnucleoside Reverse Transcriptase Inhibitor-Based Therapy in HIV-Infected Children with Perinatal Exposure to Single-Dose Nevirapine
AIDS Research and Human Retroviruses, 10/15/09 Relevance Score: 83%

Risk of Extended Viral Resistance in Human Immunodeficiency Virus-1-Infected Mozambican Children After First-Line Treatment Failure
The Pediatric Infectious Disease Journal, 11/17/09 Relevance Score: 80%