Pharmacy Medical News about Adolescent Migraine Disorders Botulinum Toxin Type A

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Botox Treatment for Migraine and Chronic Daily Headache in Adolescents
Journal of Neuroscience Nursing, 10/27/09

Chan VW et al. – The authors treated 12 adolescents (aged 14 to 18 years) with Botox injections for migraine and chronic daily headache. Six patients were in long–term treatment and received Botox in the standard "migraine" and "follow–the–pain" patterns every 3 months. Effectiveness was evaluated using pain scales and a standardized quality–of–life survey at baseline and prior to each treatment session. Duration of treatment was 3–29 months. Each patient had 9–63 injections per treatment. All 6 long–term patients reported improvement in headache symptoms, with decreases on pain scales and an average of 33%–75% improvement in quality of life. Two long–term patients had complete relief of headaches between injection series. Four patients had only one series of injections with good results. Two patients had no improvement and refused additional injections. Side effects were mild ptosis, blurred vision, hematoma at neck injection site with tingling in one arm lasting 24 hours, and burning sensations at all injection sites which lasted 1 week.

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