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Bendamustine: A New Treatment Option for Chronic Lymphocytic Leukemia
Pharmacotherapy, 10/27/09

Glode AE et al. – Bendamustine is a new agent that was recently added to the available regimens for the treatment of CLL. It was also recently approved for the treatment of non–Hodgkin's lymphoma. Its mechanism of action is unknown, but it contains an alkylating group similar to that of other bifunctional alkylating agents such as chlorambucil, and it also contains a benzimidazole central ring thought to exhibit antipurine–like properties.

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Daunorubicin Versus Mitoxantrone Versus Idarubicin as Induction and Consolidation Chemotherapy for Adults With Acute Myeloid Leukemia: The EORTC and GIMEMA Groups Study AML-10
Journal of Clinical Oncology, 10/23/09 Relevance Score: 91%

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives
Current Opinion in Oncology, 10/14/09 Relevance Score: 90%

Genetic lesions in chronic lymphocytic leukemia: clinical implications
Current Opinion in Oncology, 10/14/09 Relevance Score: 89%

Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response, a study of the GIMEMA CML WP
Blood, 10/09/09 Relevance Score: 89%

Minor histocompatibility antigens-targets of graft versus leukemia responses
International Journal of Hematology, 10/07/09 Relevance Score: 89%