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Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma
The Journal of Thoracic and Cardiovascular Surgery, 10/27/09
Hartman ML et al. – Sirolimus appears to enhance the cytotoxicity of cisplatin in malignant pleural mesothelioma cell lines through the mammalian target of rapamycin pathway. These results provide a basis for the clinical evaluation of combined sirolimus and cisplatin chemotherapy in malignant pleural mesothelioma.
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