Pharmacy Medical News about Brain-Derived Neurotrophic Factor

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SR 57746A/xaliproden, a non-peptide neurotrophic compound: prospects and constraints for the treatment of nervous system diseases
Expert Opinion on Investigational Drugs, 10/26/09

Porzner M et al. – This article reviews the preclinical and clinical data on SR 57746A and points out potential future applications of this compound. However, due to disapointing results in phase III trials, Sanofi–Aventis recently decided to discontinue the development of this drug.

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Site-Specific Antidepressant Effects of Repeated Subconvulsive Electrical Stimulation: Potential Role of Brain-Derived Neurotrophic Factor
Biological Psychiatry, 11/05/09 Relevance Score: 79%

The signaling pathway leading to ERK5 activation via G-proteins and ERK5-dependent neurotrophic effects
Molecular Pharmacology, 11/04/09 Relevance Score: 79%

Brain-derived neurotrophic factor gene polymorphisms and serum levels in Chinese atopic dermatitis patients
Journal of the European Academy of Dermatology and Venereology, 10/26/09 Relevance Score: 79%

Interaction between genetic polymorphisms and stressful life events in first episode depression
Journal of Affective Disorders, 11/11/09 Relevance Score: 78%

Effects of Neurotrophic Factors on Growth and Glial Cell Alignment of Cultured Adult Spiral Ganglion Cells
Audiology & Neuro-Otology, 10/23/09 Relevance Score: 66%