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Sigma-1 receptors regulate Bcl-2 expression by ROS-dependent transcriptional regulation of NF-kB
Journal of Pharmacology and Experimental Therapeutics, 10/28/09
Meunier J et al. – The findings thus suggest that Sig–1Rs promote cell survival, at least in part, by transcriptionally regulating Bcl–2 expression via the ROS–NF–kB pathway.
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