Pharmacy Medical News about Arsenic

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Arsenic trioxide as first-line treatment for acute promyelocytic leukemia
American Journal of Health-System Pharmacy, 10/26/09

Leu L et al. – Arsenic trioxide, alone or in combination with tretinoin, as first–line therapy in newly diagnosed APL has resulted in high rates of complete remission and molecular remission. Arsenic trioxide combined with tretinoin has shortened the time to achieve complete remission and lengthened disease–free survival, findings that suggest the usefulness of the regimen as first–line treatment for APL.

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Arsenic exposure predicts bladder cancer survival in a US population
World Journal of Urology, 10/26/09 Relevance Score: 87%

Critical Cysteine Residues of Kelch-Like ECH-Associated Protein 1 in Arsenic-Sensing and Suppression of Nuclear Factor Erythroid 2-Related Factor 2
Journal of Pharmacology and Experimental Therapeutics, 10/09/09 Relevance Score: 83%

The Effect of MAPK Inhibitors on Arsenic Trioxide-treated Calu-6 Lung Cells in Relation to Cell Death, ROS and GSH Levels
Anticancer Research, 11/10/09 Relevance Score: 80%

Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia - triggering the differentiation syndrome
Blood, 11/02/09 Relevance Score: 80%

Epigenetics: Origins and implications for cancer epidemiology
Medical Hypotheses, 10/13/09 Relevance Score: 77%