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Serotonergic and Noradrenergic Modulation of Emotion Processing by Single Dose Antidepressants
Neuropsychopharmacology, 10/29/09

Brühl AB et al. – The functional network involved in emotional information processing could be modulated by the acute application of selective noradrenergic and serotonergic drugs revealing a noradrenergic effect in thalamic and frontal areas, and a prefrontal and insular focus of serotonergic modulation. These findings could have implications for future selection criteria concerning personalized antidepressant medication in depression.

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Glutamate-based antidepressants: 20 years on
Trends in Pharmacological Sciences, 10/29/09 Relevance Score: 66%

The Role of Sodium Channels in the Mechanism of Action of Antidepressants and Mood Stabilizers
Current Drug Targets, 10/30/09 Relevance Score: 64%

Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes
Journal of Pharmacology and Experimental Therapeutics, 10/26/09 Relevance Score: 64%

Early induction of CREB activation and CREB-regulating signalling by antidepressants
International Journal of Neuropsychopharmacology, 10/21/09 Relevance Score: 64%

Vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression
Expert Opinion on Investigational Drugs, 10/02/09 Relevance Score: 64%