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A novel method for determining the inhibitory potential of anti-HIV drugs
Trends in Pharmacological Sciences, 10/29/09

Shen L et al. – Instantaneous inhibitory potential has been derived as a new measure of antiviral drug activity. IIP incorporates the slope parameter and thus is a more accurate pharmacodynamic measure of antiviral activity than current measures such as IC50 and inhibitory quotient. Determining how to use IIP to predict the in vivo efficacy of anti–HIV–1 drugs is nevertheless important. This article discusses recent advances in in vitro measures of antiviral activity and the therapeutic implications of the dose–response curve slope and IIP.

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Effectiveness of Increasing Emergency Department Patients' Self-perceived Risk for Being Human Immunodeficiency Virus (HIV) Infected Through Audio Computer Self-interview–based Feedback About Reported HIV Risk Behaviors
Academic Emergency Medicine, 11/11/09 Relevance Score: 95%

HIV-Specific Health Care Utilization and Mortality among Tuberculosis/HIV Coinfected Persons
AIDS Patient Care and STDs, 10/06/09 Relevance Score: 95%

Mediators of HIV-related stigma and risk behavior in HIV infected young women
AIDS Care, 11/12/09 Relevance Score: 94%

Sperm May Play Leading Role In Spreading HIV
ScienceDaily, 10/27/09 Relevance Score: 94%

Female sex work and HIV risks in Croatia
AIDS Care, 10/29/09 Relevance Score: 93%