Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Statins and cancer risk
Your Article Summary
See Latest ArticlesThe human ADFP gene is a direct LXR target gene and differentially regulated by synthetic LXR ligands
Molecular Pharmacology, 11/02/09
Kotokorpi P et al. – The results show that sequence identity of the hexamer repeats in DR4 elements is not sufficient to determine if the element binds or not binds LXR. The partial agonist GW3965 specifically regulates ADFP gene transcription and the data prove that the two synthetic LXR agonists, commonly used in experimental research, can differentially regulate gene expression. This has implications for pharmaceutical targeting of LXR.
Related Articles
Insights into the pathogenesis of axial spondyloarthropathy based on gene expression profiles
Arthritis Research & Therapy, 11/13/09
Relevance Score: 67%
Single nucleotide polymorphisms of complement component 5 and periodontitis
Journal of Periodontal Research, 11/11/09
Relevance Score: 67%
Can Autoimmunity Against Calsequestrin Explain the Eye and Eyelid Muscle Inflammation of Thyroid Eye Disease?
Orbit - The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery, 11/12/09
Relevance Score: 65%
FCRL3, an Autoimmune Susceptibility Gene, Has Inhibitory Potential on B-Cell Receptor-Mediated Signaling
Journal of Immunology, 10/23/09
Relevance Score: 65%
Multifaceted Evasion of the Interferon Response by Cytomegalovirus
Journal of Interferon & Cytokine Research, 10/07/09
Relevance Score: 65%
Today in Basic Science...keeping you current
Receive free subspecialty "5-minute updates" via email
Voltage-gated sodium channels in nociception and their potential as targets for new drugs in treatment of chronic neuropathic pain
Current Anaesthesia and Critical Care, 11/24/09
Population impact of regulatory activity restricting prescribing of COX-2 inhibitors: ecological study
British Journal of Clinical Pharmacology, 11/24/09
Interactions between morphine and nitric oxide in various organs
Journal of Anesthesia, 11/24/09
Sponsor
Article Search
Sponsor