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Corticotropin Releasing Factor (CRF) Sensitization of Ethanol Withdrawal-Induced Anxiety-like Behavior is Brain Site Specific and Mediated by CRF-1 Receptors: Relation to Stress-Induced Sensitization
Journal of Pharmacology and Experimental Therapeutics, 10/26/09
Huang MM et al. – The results indicate that CRF released by stress acts on CRF–1 receptors within specific brain regions to produce a cumulative adaptation that sensitizes anxiety–like behavior during withdrawal from chronic ethanol exposure.
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