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Trends in prescribing and self-poisoning in relation to UK regulatory authority warnings against use of SSRI antidepressants in under-18-year-olds
British Journal of Clinical Pharmacology, 11/02/09
Bergen H et al. – The reduction in both prescribing and self–poisoning with SSRI antidepressants (except fluoxetine) following the MHRA warning is in keeping with reduced availability of these drugs. There was some evidence of substitution from other SSRIs to fluoxetine for use in self–poisoning. Importantly, overall rates of nonfatal self–harm and self–poisoning did not change, indicating no substitution of method or increases in self–injury.
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