Pharmacy Medical News about Capsaicin Pain Models, Neurological

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Debunking Myths in the US Healthcare System

5. Statins and cancer risk

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

A comparison of two formulations of intradermal capsaicin as models of neuropathic pain in healthy volunteers
British Journal of Clinical Pharmacology, 10/16/09

Gustafsson H et al. – Intradermal capsaicin has some utility as a model of neuropathic pain. Dose–response relationships have not been well documented. Two formulations have previously been used but their performance has not been compared...The formulations are comparable over the dose range 1–30 microg. The significantly lower pain response at the 100 microg dose in the Tween compared with the HP–?–CD formulation is likely to be due to limitations in solubility at the 100 microg level. Given the greater ease of formulation and the superior dose–response relationship, the HP–?–CD formulation is preferable for use in the model in future studies.

<< Previous
The Effect of Oral Methadone on the QTc Interval in Advanced...

Next >>
An open-label, 1-year extension study of the long-term safety and...