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Immunoallergic Drug-Induced Liver Injury in Humans
Seminars in Liver Disease, 10/16/09
Uetrecht J – A drug can induce an immune response to a reactive metabolite acting as a hapten; in others, the response is against a native protein, which leads to an autoimmune reaction. This is likely responsible for the interindividual differences in susceptibility and outcome noted in human DILI.
Today in Adverse Drug Reactions...keeping you current
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