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See Latest ArticlesPros and cons of antibiotic therapy for pouchitis
Expert Review of Gastroenterology & Hepatology, 10/13/09
Navaneethan U et al. – Pouchitis is the most common long–term complication of ileal pouch–anal anastomosis in patients with ulcerative colitis, with a cumulative prevalence of up to 50%. The pathogenesis of pouchitis is probably associated with alterations in commensal bacterial flora, and most patients with pouchitis respond favorably to antibiotic therapy. Antibiotic therapy is the mainstay of treatment for active pouchitis, with ciprofloxacin or metronidazole traditionally being first–line agents.
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