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See Latest ArticlesLimited Sampling Models and Bayesian Estimation for Mycophenolic Acid Area under the Curve Prediction in Stable Renal Transplant Patients Co-Medicated with Ciclosporin or Sirolimus
Clinical Pharmacokinetics, 10/15/09
Musuamba FT et al. – Use of the developed multiple linear regression equation and Bayesian estimator, both based on only three blood sampling times within 2 hours following a dose of mycophenolate mofetil, allowed an accurate prediction of a patient's MPA AUC12 for therapeutic drug monitoring and dose individualization. These findings should be validated in a randomized prospective trial.
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