Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. Statins and cancer risk
Your Article Summary
See Latest ArticlesSynthesis and pharmacological properties of a new fluorescent opioid peptide analog
Pharmacological Reports, 10/12/09
Lukowiak M et al. – This paper reports the pharmacological properties of a new analog in which one pharmacophore of biphalin was replaced with fluorescent 7–succinylamido–4–methyl–coumarin. The resulting compound displays an affinity for mu opioid receptors that is a delta opioid receptor comparable to biphalin but with an affinity that is over a hundred times lower. This mu opioid selective fluorescent peptide analog could be applied in pharmacokinetic and pharmacodynamic studies of biphalin related analogs.
Related Articles
Morphine/naltrexone extended-release capsules (Embeda): Combination of mu-opioid agonist and mu-opioid antagonist approved for the management of moderate-to-severe pain when continuous analgesia is needed for an extended time period
Formulary, 11/02/09
Relevance Score: 94%
Comparison of the Anti-nociceptive and Anti-Rewarding Profiles of Novel Bifunctional Nociceptin/Orphanin FQ Receptor (NOPr)-Mu Opioid Receptor (MOPr) Ligands: Implications for Therapeutic Applications
Journal of Pharmacology and Experimental Therapeutics, 10/07/09
Relevance Score: 94%
Adolor Corporation Initiates Clinical Testing in Opioid Bowel Dysfunction Program
Adolor Corporation, 11/13/09
Relevance Score: 93%
Tapentadol immediate release for the relief of moderate-to-severe acute pain
Expert Opinion in Pharmacotherapy, 10/08/09
Relevance Score: 93%
Tapentadol hydrochloride: A next-generation, centrally acting analgesic with two mechanisms of action in a single molecule
Drugs of Today, 10/19/09
Relevance Score: 91%
Today in Pain Management...keeping you current
Receive free subspecialty "5-minute updates" via email
Out-of-pocket Prices of Opioid Analgesics in the United States, 1999–2004
Pain Medicine, 12/10/09
Opioids for the Management of Severe Chronic Nonmalignant Pain in Children: A Retrospective 1 Year Practice Survey in a Childrens Hospital
Pain Medicine, 12/10/09
An Open Pilot Study Assessing the Benefits of Quetiapine for the Prevention of Migraine Refractory to the Combination of Atenolol, Nortriptyline, and Flunarizine
Pain Medicine, 12/10/09
Sponsor
Article Search
Sponsor
Sponsor