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A safety and feasibility study comparing an intermittent high dose with a daily standard dose of liposomal amphotericin B for persistent neutropenic fever
Journal of Medical Microbiology, 10/21/09
Ellis M et al. – This feasibility study suggests that a short intermittent high–dose course of 10/5/5 mg LAB kg–1 on days 1, 3 and 6 may be as safe and effective as a standard 14 day course of 3 mg kg–1 per day, with drug–acquisition cost savings and reduced drug exposure. A larger study is indicated for confirmation of this.
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