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Upper gastrointestinal tolerability of alendronate sodium monohydrate 10 mg once daily in postmenopausal women: A 12-week, randomized, double-blind, placebo-controlled, exploratory study
Clinical Therapeutics, 10/15/09

Adachi JD et al. – In these postmenopausal women who received ALN monohydrate or placebo, upper GI AEs were common (20.4%–22.7%). The proportion of patients who experienced upper GI AEs considered drug related or that led to discontinuation was appar– ently greater with ALN monohydrate compared with placebo.


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