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See Latest ArticlesSignificance of thymidylate synthase for resistance to pemetrexed in lung cancer
Cancer Science, 10/23/09
Ozasa H et al. – The alteration of molecular pharmacological factors in relation with pemetrexed resistance is dose–dependent, and that up–regulation of the expression of the TS gene may have an important role in the acquired resistance to pemetrexed. In addition, TS may be a predictive marker for pemetrexed sensitivity in lung cancer.
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