Pharmacy Medical News about Chronic Disease Kidney Diseases Vitamin D Dialysis

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Vitamin D compounds for people with chronic kidney disease requiring dialysis
Cochrane Reviews, 10/20/09

Palmer SC et al. – The authors identified 60 studies of vitamin D preparations in people with CKD and requiring dialysis involving 2773 people. No studies were designed to understand the effect of vitamin D therapy on risks of death. Vitamin D agents suppress parathyroid hormone (PTH) significantly compared with no treatment, however also increase both circulating calcium and phosphorus levels. Intravenous vitamin D may lower PTH more than oral vitamin D. Few studies directly compare newer vitamin D therapies with earlier (and presently more common treatment options; calcitriol and alfacalcidol); newer treatment options therefore cannot be recommended as superior to established treatments.

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