Pharmacy Medical News about Pain, Postoperative Ketoprofen Dexketoprofen

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Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults
Cochrane Reviews, 10/08/09

Barden J et al. – A single dose of ketoprofen 25 mg to 100 mg provides a high level of pain relief to 60% to 70% of those with moderate or severe postoperative pain. It has similar efficacy to other commonly used analgesics at standard doses, including ibuprofen and naproxen, with a duration of action around 5 hours. Single dose dexketoprofen at 10 mg to 25 mg provides a high level of pain relief to 45% to 50% of patients for about 4 hours. Adverse events were generally mild to moderate in severity, and no more common with either drug than with placebo in these singe dose studies.

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Acute postoperative pain as a risk factor for chronic pain after surgery
European Journal of Pain, 11/12/09 Relevance Score: 72%

The Role of Catastrophizing in the Prediction of Postoperative Pain
Pain Medicine, 10/29/09 Relevance Score: 70%

A multicenter, randomized, double-blind, placebo- controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain
Clinical Therapeutics, 10/23/09 Relevance Score: 70%

Behavioral Indicators of Postoperative Pain in Older Adults With Delirium
Clinical Nursing Research, 10/12/09 Relevance Score: 70%

Effects of preoperative lornoxicam versus tramadol on postoperative pain and adverse effects in adult tonsillectomy patients
Agri, 10/01/09 Relevance Score: 69%