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Garimella PS et al. – This review of eight trials evaluated naftopidil for the treatment of BPH. Current evidence is sparse. The authors did not identify any placebo–controlled trials. Naftopidil had a similar short–term efficacy and adverse–effect profile compared to low–dose tamsulosin, and better efficacy than phytotherapy (eviprostat). Adverse effects of naftopidil were few, most commonly dizziness and hypotension. Prior to wide–spread use, more long–term, randomized, controlled studies compared to standard therapy are needed.

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