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Branski LK et al. – Innovations in fluid management, ventilatory support, surgical care, and antimicrobial therapy have contributed to a significant reduction in morbidity and mortality rates in burn patients. Vancomycin and clindamycin are the two most important reserve antibiotics for methicillin–resistant Staphylococcus aureus infection. Oxazolidinones and streptogramins have showed high effectiveness against gram–positive infections. Colistin has re–emerged as a highly effective antibiotic against multiresistant Pseudomonas and Acinetobacter infections. Current challenges include Candida, Aspergillus, and molds.

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