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See Latest ArticlesIdentification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite
Drug Metabolism and Disposition, 10/09/09
Kazui M et al. – The results help explain the role of genetic polymorphism of CYP2C19 and also the effect of potent CYP3A inhibitors on the pharmacokinetics and pharmacodynamics of clopidogrel in humans, and on clinical outcomes.
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