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Gastrointestinal Safety of Nonsteroidal Antiinflammatory Drugs and Selective Cyclooxygenase-2 Inhibitors in Patients on Warfarin
Annals of Pharmacotherapy, 10/13/09
Cheetham TC et al. – In general, nonselective NSAIDs and selective COX–2 inhibitors should be avoided in patients taking warfarin. In situations where patients require NSAIDs and cannot be managed using other therapies, The results suggest that selective COX–2 inhibitors are associated with fewer hospitalizations for GI bleeding.
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