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Pharmacological Removal of hERG Potassium Channel Inactivation by ICA-105574
Molecular Pharmacology, 10/12/09
Gerlach AC et al. – The authors have identified a novel agent that can prevent inactivation of hERG potassium channels. This compound may provide a useful tool to further understand the mechanism by which hERG channels inactivate and affect cardiac function in addition to the role of hERG channels in other cell systems.
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