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Two different approaches for the prediction of In Vivo plasma concentration-time profile from In Vitro release data of once daily formulations of diltiazem hydrochloride
Archives of Pharmacal Research, 10/14/09
Bendas ER – The percent dissolved data from the two formulations were used as input function to predict the in vivo plasma data by the two approaches. The two methods were validated by prediction of plasma data from in vitro release data of FDA approved 300 mg extended release capsule. Prediction errors were estimated for C max and area under the curve (AUC) to determine the validity of the methods. The percent prediction error for each parameter is not exceeding 15%.
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FDA Approves Gardasil to Prevent Genital Warts in Males. Agency Also Approves Bivalent HPV Vaccine for Girls, Young Women
American Family Physician, 10/22/09
Novartis receives FDA approval for Valturna®, a single-pill combination of valsartan and aliskiren, to treat high blood pressure
Novartis, 09/18/09
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Salix Pharmaceuticals, 09/10/09
Today in Other Drugs...keeping you current
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Doxycycline for osteoarthritis of the knee or hip
Cochrane Reviews, 10/23/09
Effect of Rosiglitazone, Metformin, and Glyburide on Bone Biomarkers in Patients with Type 2 Diabetes
Journal of Clinical Endocrinology and Metabolism, 11/10/09
A New Drug in a New Class for Postmenopausal Osteoporosis
The Female Patient, 11/11/09
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