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See Latest ArticlesQuantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries
Drug Metabolism and Disposition, 10/06/09
Srivastava A et al. – This is the first evidence for metabolic activation of nevirapine in humans, and only the second minimum estimate in patients of bioactivation of a widely prescribed drug associated with idiosyncratic toxicities. The method can be used as a template for comparative estimations of bioactivation of any drug in patients.
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