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See Latest ArticlesGlutathione S-transferase Catalyzed Desulfonylation of a Sulfonylfuropyridine
Drug Metabolism and Disposition, 10/05/09
Bateman TJ et al. – A mechanism is proposed involving direct nucleophilic addition of GSH to sulfonylfuropyridine, resulting in an unstable adduct which spontaneously decomposes to form M1 and M2.
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