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The third Symptom Management Research Trial in Oncology (SMaRT Oncology-3): a randomised trial to determine the efficacy of adding a complex intervention for major depressive disorder (Depression Care for People with Lung Cancer) to usual care, compared to usual care alone in patients with lung cancer
Trials, 10/05/09

Walker J et al. – Randomisation will be carried out by telephoning a secure computerised central randomisation system or by using a secure web interface. The primary outcome measure is average depression severity. This will be assessed using scores on the 20–item Symptom Hopkins Checklist (SCL–20D), collected every four weeks over 32 weeks. Secondary outcomes include severity of anxiety, pain and fatigue; self–rated improvement of depression; quality of life and satisfaction with depression care.

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