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Ross S et al. – Opiate addiction is treated by approved agonist and antagonist mu–opioid medications with the future potential for agents that can modulate the stress systems and the iboga alkaloids. Although no pharmacotherapies are currently approved for cocaine addiction, promising lines of research include agents that affect dopaminergic, GABAergic, serotonergic, and glutamatergic systems as well as the promise for immune therapies.

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