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See Latest ArticlesHow important is intestinal cytochrome P450 3A metabolism
Trends in Pharmacological Sciences, 10/14/09
Herwaarden AEV et al. – Cytochrome P450 3A (CYP3A) enzymes metabolize a wide variety of xenobiotics including many drugs. Because CYP3A is localized in both the liver and intestine, it can make a major contribution to the presystemic elimination of substrate drugs after oral administration. However, assessments of the relative importance of intestinal versus hepatic CYP3A–mediated first–pass metabolism have been difficult to make and are subject to extensive discussion.
Today in Antimicrobials...keeping you current
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Drugs for preventing malaria in travellers
Cochrane Reviews, 10/22/09
Antibiotic Prophylaxis and Recurrent Urinary Tract Infection in Children
New England Journal of Medicine, 10/29/09
Comparison of Gentamicin and Mupirocin in the Prevention of Exit-Site Infection and Peritonitis in Peritoneal Dialysis
Advances in Peritoneal Dialysis, 10/20/09
Today in Basic Science...keeping you current
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Opiate-induced hypernociception and chemokine receptors
Neuropharmacology, 11/10/09
Ketorolac But Not Morphine Exerts Inflammatory and Metabolic Effects in Synovial Membrane After Knee Arthroscopy: A Double-Blind Randomized Prospective Study Using the Microdialysis Technique
Regional Anesthesia and Pain Medicine, 11/04/09
Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1
Current Drug Targets, 11/03/09
Today in Stomach/GI...keeping you current
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Salix Receives FDA Marketing Approval for Metozolv
Salix Pharmaceuticals, 09/10/09
Methotrexate for maintenance of remission in Crohn's disease
Cochrane Reviews, 10/27/09
Monotherapy versus combination therapy for the treatment of chronic hepatitis B
Expert Opinion on Investigational Drugs, 10/26/09
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