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Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies
Trends in Pharmacological Sciences, 10/15/09
Shetty S et al. – Adiponectin might, therefore, be a viable protein therapeutic that could be supplied in a recombinant form in the context of type 2 diabetes and cardiovascular disease. However, the high abundance, complex tertiary and quaternary structure and rapid turnover might make chronic administration of the protein rather challenging.
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