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See Latest ArticlesCurrent data of targeted therapies for the treatment of triple-negative advanced breast cancer: empiricism or evidence-based
Expert Opinion on Investigational Drugs, 10/02/09
Petrelli F et al. – Treatment of TN BC is more empirical than evidence–based. The cornerstone of treatment is chemotherapy, but in the near future, novel target agents will emerge as possible partners.
Fausto Petrelli, 10/03/09
| Tre treatment of triple-receptor negative breast cancer is a challenge for medical oncologist standind the lack of a real “target” to hit. Up today none exist other than standard chemotherapy, the disease respond very well but the prognosis is however poor. Why a so chemosensitive disease retains so bad outcome? Is there a critical target useful for therapeutic purpose? Much work has been done to look for it (EGFR, VEGF, c-Kit, BRCA, DNA..) and a plethora of target therapies has been tested in this setting. We have reviewed all agents and studies available up today used in triple negative advanced breast cancer. As the readers will see this strategy is not yet winning for these unfortunately patients. |
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