Pharmacy Medical News about Myofascial Pain Syndromes Thiocolchicoside

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The efficacy of topical thiocolchicoside (Muscoril) in the treatment of acute cervical myofascial pain syndrome: a single-blind, randomized, prospective, phase IV clinical study
Agri, 10/01/09

Ketenci A et al. – Thiocolchicoside can be used in the treatment of myofascial pain syndrome. The ointment form may be a good alternative, particularly in patients who cannot receive injections.

Methods

65 patients with acute myofascial pain syndrome were recruited into the study.
Patients were randomized into three groups. The first group received thiocolchicoside ointment onto the trigger points, the second group received 8 mg thiocolchicoside intramuscular injection to the trigger points, and the third group received both treatments.
Treatment was applied for 5 consecutive days.
Algometric and goniometric measurements and pain severity assessments with visual analog scale (VAS) were repeated on the first, third, and fifth days of the treatment.

Results

Pain severity measured with VAS significantly improved after the first day in the mono–therapy groups and after the third day in all groups.
While significant improvement was observed in all three groups in right lateral flexion measurements, no significant changes were observed in the combined treatment group in left lateral flexion measurements.

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