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Investigational drugs targeting FLT3 for leukemia
Expert Opinion on Investigational Drugs, 09/29/09
Ustun C et al. – The authors focus on the preclinical data demonstrating in vitro activity, inhibition of downstream signaling pathways and potential synergy with traditional chemotherapeutic agents. Also, early clinical trial data specifically focusing on drug toxicity, clinical efficacy and future directions of FLT3–directed anticancer therapy are discussed.
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