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Generic substitution: additional challenge for adherence in hypertensive patients
Current Medical Research and Opinion, 09/29/09

Hakonsen H et al. – This study shows that generic substitution can be an additional factor in poor drug adherence in hypertensive patients and contributes to concerns and confusion among the patients. Although generic substitution is an important measure of cost containment, health personnel should approach each patient individually. Clearly, many patients feel insecure about substituting their medication and demand more information.

Exclusive Author Commentary
Helle Hakonsen, Else-Lydia Toverud, 10/09/09

We would like to emphasize how important it can be that the patients are in a position to show which drugs they are currently using. If other interview methods are being used (e.g. questionnaires by mail) this kind of misappropriate drug use might not be detected. This possible part of their true drug consumption will be even more overshadowed if the only source for the research is a prescription register database.

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